Mon,01May2017

Dr. Péter Nagy

Head Department of Molecular Immunology and Toxicology; Deputy Director of International relations
Department of Molecular Immunology and Toxicology,
National Institute of Oncology,
Ráth György utca 7-9,
Budapest, Hungary, 1122
Tel.: +36-1-224-8600/3644
Fax: +36-1-224-8620
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Research interests

  • Thermodynamic and kinetic aspects of cysteine oxidation and hydrogen sulfide biological chemistry
  • Coordination and redox chemistry of thiols including hydrogen sulfide
  • Thiol oxidation in redox signaling
  • Redox regulation of hydrogen sulfide biology

Selected Recent Publications

  • Péter Nagy* Kinetics and Mechanisms of Thiol-Disulfide Exchange Covering Direct Substitution and Thiol Oxidation-Mediated Pathways Antioxidants and Redox Signaling Thiol-Disulfide Exchange Forum Issue (2013) Invited review epub
  • Péter Nagy Thomas P. Lechte, Andrew B. Das and Christine C. Winterbourn     Conjugation of Glutathione to Oxidized Tyrosine Residues in Peptides and Proteins Journal of Biological Chemistry (2012) 287, 26068-76.     Spotlighted in Chemical Research in Toxicology (2012) 25, 1544
  • Péter Nagy* Amir Karton, Andrea Betz, Alexander V. Peskin, Paul Pace, Robert O'Reilly, Mark B. Hampton, Leo Radom, and Christine C. Winterbourn Model for the Exceptional Reactivity of Peroxiredoxins 2 and 3 with Hydrogen Peroxide; A Kinetic and Computational Study Journal of Biological Chemistry (2011) 286, 18048-55
  • Péter Nagy* and Christine C. Winterbourn Rapid Reaction of Hydrogen Sulfide with the Neutrophil Oxidant Hypochlorous Acid to Generate Polysulfides Chemical Research in Toxicology Rapid Reports ("reserved for timely topics of unusual interest") (2010) 23, 1541-1543
  • Péter Nagy* and Christine C. Winterbourn Redox chemistry of biological thiols Advances in Molecular Toxicology, Fishbein, JC., Ed. Elsevier, (2010), 4,pp. 183-222

ESF

COST

POLICY STATEMENT: Biomedicine and Molecular Biosciences Action BM1005 is funded by COST, through its implementing agent the European Science Foundation.