Home The Action Management Committee Giuseppe Cirino (IT)


Giuseppe Cirino, PhD FBPharmacolS

Prof. Ordinario Farmacologia
Preside Facoltà Farmacia
Dipartimento di Farmacologia Sperimentale,
Università di Napoli Federico II,
Via Domenico Montesano 49
80131, Napoli
Tel: +39 081-679934; +39081-678102
Fax: +39 081-678107-403

Research interests
Dr. Cirino's research focuses on cardiovascular pharmacology and immunopharmacology. He is involved in the design, synthesis and pharmacological characterization of novel gasotransmitter-releasing molecules in vitro and in vivo.  He also studies the role of H2S in the pathogenesis and vascular complications of diabetes and other vascular diseases.  He is a leading expert in erectile dysfunction and is working to improve our understanding of the role of NO and H2S, and their interactions in this condition.

Selected Recent Publications

  • d'Emmanuele di Villa Bianca R, Sorrentino R, Mirone V, Cirino G. Hydrogen sulfide and erectile function: a novel therapeutic target. Nat Rev Urol. 2011; 8:286-9.
  • Caliendo G, Cirino G, Santagada V, Wallace JL. Synthesis and biological effects of hydrogen sulfide (H2S): development of H2S-releasing drugs as pharmaceuticals. J Med Chem. 2010; 53:6275-86.
  • Wallace JL, Caliendo G, Santagada V, Cirino G. Markedly reduced toxicity of a hydrogen sulphide-releasing derivative of naproxen (ATB-346). Br J Pharmacol. 2010; 159:1236-46.
  • d'Emmanuele di Villa Bianca R, Sorrentino R, Maffia P, Mirone V, Imbimbo C, Fusco F, De Palma R, Ignarro LJ, Cirino G. Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation. Proc Natl Acad Sci U S A. 2009;106:4513-8
  • Bucci M, Mirone V, Di Lorenzo A, Vellecco V, Roviezzo F, Brancaleone V, Ciro I, Cirino G. Hydrogen sulphide is involved in testosterone vascular effect. Eur Urol. 2009; 56:378-83.




POLICY STATEMENT: Biomedicine and Molecular Biosciences Action BM1005 is funded by COST, through its implementing agent the European Science Foundation.