European Network on Gasotransmitters

Hot Papers of September 2015-January 2016 - Hot Papers of the September-December 2014

 Hot papers of September-December 2014

• Zhu LJ, Li TY, Luo CX, Jiang N, Chang L, Lin YH, Zhou HH, Chen C, Zhang Y, Lu W, Gao LY, Ma Y, Zhou QG, Hu Q, Hu XL, Zhang J, Wu HY,Zhu DY. CAPON-nNOS coupling can serve as a target for developing new anxiolytics. Nat Med. 2014;20(9):1050-4. doi: 10.1038/nm.3644.
• Gill AJ, Kovacsics CE, Cross SA, Vance PJ, Kolson LL, Jordan-Sciutto KL, Gelman BB, Kolson DL. Heme oxygenase-1 deficiency accompanies neuropathogenesis of HIV-associated neurocognitive disorders. J Clin Invest. 2014;124(10):4459-72. doi: 10.1172/JCI72279.
• Ereño-Orbea J, Majtan T, Oyenarte I, Kraus JP, Martínez-Cruz LA. Structural insight into the molecular mechanism of allosteric activation of human cystathionine β-synthase by S-adenosylmethionine. Proc Natl Acad Sci U S A. 2014;111(37):E3845-52. doi: 10.1073/pnas.1414545111.
• Elies J, Scragg JL, Huang S, Dallas ML, Huang D, MacDougall D, Boyle JP, Gamper N, Peers C. Hydrogen sulfide inhibits Cav3.2 T-type Ca2+ channels. FASEB J. 2014;28(12):5376-87. doi: 10.1096/fj.14-257113. 
• Wegiel B, Larsen R, Gallo D, Chin BY, Harris C, Mannam P, Kaczmarek E, Lee PJ, Zuckerbraun BS, Flavell R, Soares MP, Otterbein LE. Macrophages sense and kill bacteria through carbon monoxide–dependent inflammasome activation. J Clin Invest. 2014;124(11):4926-40. doi: 10.1172/JCI72853.
• Tawfik A, Markand S, Al-Shabrawey M, Mayo JN, Reynolds J, Bearden SE, Ganapathy V, Smith SB. Alterations of retinal vasculature in cystathionine-β-synthase heterozygous mice: a model of mild to moderate hyperhomocysteinemia. Am J Pathol. 2014;184(9):2573-85. doi: 10.1016/j.ajpath.2014.05.018.
• Wilkins MR, Aldashev AA, Wharton J, Rhodes CJ, Vandrovcova J, Kasperaviciute D, Bhosle SG, Mueller M, Geschka S, Rison S, Kojonazarov B, Morrell NW, Neidhardt I, Surmeli NB, Aitman TJ, Stasch JP, Behrends S, Marletta MA. α1-A680T Variant in GUCY1A3 as a Candidate Conferring Protection From Pulmonary Hypertension AmongKyrgyz Highlanders. Circ Cardiovasc Genet. 2014;7(6):920-9. doi: 10.1161/CIRCGENETICS.114.000763.
• Vasas A, Dóka É, Fábián I, Nagy P. Kinetic and thermodynamic studies on the disulfide-bond reducing potential of hydrogen sulfide. Nitric Oxide. 2014 Dec 12. pii: S1089-8603(14)00510-2. doi: 10.1016/j.niox.2014.12.003.
• Zamani P, Rawat D, Shiva-Kumar P, Geraci S, Bhuva R, Konda P, Doulias P, Ischiropoulos H, Townsend RR, Margulies KB, Cappola TP, Poole DC, Chirinos JA. The Effect of Inorganic Nitrate on Exercise Capacity in Heart Failure with Preserved Ejection Fraction. Circulation. 2014 Dec 22. pii: CIRCULATIONAHA.114.012957.
• Hu Y, Li R, Yang H, Luo H, Chen Z. Sirtuin 6 Is Essential for Sodium Sulfide-mediated Cytoprotective Effect in Ischemia/Reperfusion-Stimulated Brain Endothelial Cells. J Stroke Cerebrovasc Dis. 2014. pii: S1052-3057(14)00505-9. doi: 10.1016/j.jstrokecerebrovasdis.2014.10.006.
• Hine C, Harputlugil E, Zhang Y, Ruckenstuhl C, Lee BC, Brace L, Longchamp A, Treviño-Villarreal JH, Mejia P, Ozaki CK, Wang R, Gladyshev VN, Madeo F, Mair WB, Mitchell JR. Endogenous Hydrogen Sulfide Production Is Essential for Dietary Restriction Benefits. Cell. 2014 Dec 23. pii: S0092-8674(14)01525-6. doi: 10.1016/j.cell.2014.11.048.